Human Bone Osteosarcoma Cells (U-2 OS Line)

The U-2 OS cell line, originally known as the 2T line, was derived from the bone tissue of a fifteen-year-old human female suffering from osteosarcoma. Established by J. Ponten and E. Saksela in 1964, the original cells were taken from a moderately differentiated sarcoma of the tibia.